The niche-derived glial cell line-derived neurotrophic factor (GDNF) induces migration of mouse spermatogonial stem/progenitor cells.
In mammals, the biological activity of the stem/progenitor compartment sustains production of mature gametes through spermatogenesis.Spermatogonial stem cells and their progeny belong to the class of undifferentiated spermatogonia, a germ cell population found on the basal membrane of the seminiferous tubules.A large body of evidence has demonstrat